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Overview of Prospective and Experimental Studies Despite the strong and independent relationship between homocysteine and cardiovascular disease found in the great number of retrospective case-controlled studies mentioned above, prospective cohort studies, which generally provide the most rigorous evidence, have yielded inconclusive results

Berglund, J

Acute injuries may be 80-90% healed, while chronic injuries show substantial improvement but often require additional weeks for complete resolution

See these diagrams: Source: Clinical Procedures for Safer Patient Care by Doyle & McCutcheon

Rescue of a mitochondrial deficiency causing Leber Hereditary Optic Neuropathy