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All controlled studies referenced below were conducted in cell culture (3T3-L1 adipocytes, primary muscle stem cells) or rodent models (diet-induced obese mice, aged C57BL/6J mice)
DPP-4 inhibitors are not recommended for cardiorenal risk reduction in high-risk individuals
Small number of research groups : A limited number of research groups have conducted most studies, which may affect the generalizability of the results
(n.d.) Understanding insulin resistance
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