Announced by Novo Nordisk on January 17, 2025, the randomized, double-blinded, parallel-group, placebo-controlled STEP UP trial evaluated the efficacy of semaglutide 7.2 mg to semaglutide 2.4 mg (Wegovy) and placebo in more than 1400 adults with obesity and without type 2 diabetes (T2D)
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It holds an active LegitScript certification, lists a verifiable Irvine, California, business address, names four pharmacy partners openly, and uses OpenLoop Healthcare Partners as the prescribing clinician network
The experiment was divided into sham surgery group, I/R model group, and I/R+IGF-1 LR3 treatment group (0.5mg/kg, orally administered 30 minutes before reperfusion)