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(1995a): Imipramine and fluoxetine prevent the stress-induced escape deficits in rats through a distinct mechanism of action
While proof-of-concept is firmly established in rodent models, issues such as delivery efficiency, long-term integration, and avoidance of maladaptive circuitry must be resolved to enable therapeutic implementation in the human CNS
Use care while using this high-purity unique peptide to ensure its safety
Type 2 diabetes mellitus (DM2) affects a 13.8% of the Spanish population1 and its prevalence is expected to increase in the future.2 The presence of DM2 increases significantly the risk of cardiovascular events, chronic kidney disease (CKD), and premature death3,4 and as its prevalence increases it is expected to rise the incidence of microvascular and macrovascular complications.5 Until the last decade, the control of blood glucose, blood pressure, dyslipidemia, and the use of inhibitors of the renin-angiotensin system (iSRA) have been the only strategies available to reduce cardiovascular and renal risk in this population
Identification of erythroferrone as an erythroid regulator of iron metabolism
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