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Nature Reviews Genetics, 15 (2), 107120
In keeping with the reduced capacity of homocysteine-exposed endothelial cells to inhibit platelet aggregation, Lentz and collaborators demonstrated, using experimental hyperhomocysteinemia (induced by a diet depleted of folate, high in methionine, and choline-free) that the endothelial-dependent vasodilation is impaired in hyperhomocysteinemic primates
Patients who keep symptom and medication diaries tend to show better adherence and give their clinicians far better data to work with
Contrary to popular belief, IV therapy is not painful
Both appear in research and practitioner protocols
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