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Polydatin attenuates cisplatin-induced acute kidney injury via SIRT6-mediated autophagy activation

Specific antioxidants in human milk include vitamins A, E, C, LF, lysozyme, glutathione peroxidase, SOD, catalase, ceruloplasmin, coenzyme Q10, thioredoxin, leptin, adiponectin, and trace elementsiron, copper, zinc, and selenium (69)

However supplementation of JA stimulated mRNA levels of SOD and GPX and their activities under alkaline stress and reduced overproduction of O 2 and H 2 O 2 to reduce oxidative stress 21,25

Without adequate hydration, these bound compounds cannot be cleared from the body efficiently, limiting the supplement's full detoxification benefits

doi:10.1016/j.ipha.2024.09.008