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The initial loading period for the oral form is also longer, lasting 12 weeks

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Homeostatic mechanism that tends to stabilise an upset in the bodys physiological condition by preventing an excessive response to a stimulus, typically as the stimulus is removed

This lack of delay would represent a major advantage if translatable to humans, given that conventional antidepressants typically require 2-6 weeks before patients experience relief

Cardenas internal medicine direction: Baseline/serial labs : fasting insulin/glucose, A1C, lipid panel, liver enzymes, renal function, pregnancy testing as indicated Comorbidity screening : thyroid function, prolactin, 17-OHP (PCOS differential)