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The copper ion is coordinated to the peptide through the nitrogen atoms of the glycine and histidine residues, giving the compound its distinctive blue color in crystalline form

While glutathione itself is not a peptide, researchers interested in biological signaling molecules may benefit from understanding what peptides are and how they work

The 5-on/2-off idea borrows from GH-therapy practice, where periodic breaks are used with the aim of limiting receptor down-regulation

"Structure of Trypanosoma brucei glutathione synthetase: domain and loop alterations in the catalytic cycle of a highly conserved enzyme"

Decreased consumption of branched-chain amino acids improves metabolic health