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In a 48-week phase 2 trial, intravenous bimagrumab conferred approximately a 20% reduction in fat mass and a 4.4% increase in lean mass (143)
Why it matters: Monitoring helps connect symptom changes with lab response and safe refill planning
Secretion of GH is stimulated by GH-releasing hormone (GHRH) and ghrelin (acting via the GH secretagogue [GHS] receptor [GHSR]), and inhibited by somatostatin (SRIF)
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The benzyl alcohol inhibits bacterial reproduction (bacteriostatic, not bactericidal), preventing contamination in multi-dose vials without aggressively disrupting most biological molecules
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