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In addition, there was no significant linear relationship between dose (g/day) (coefficients = 0.02, p = 0.600) and duration of intervention (weeks) (coefficients = 0.54, p = 0.578) and changes in insulin (Figures 6B, 7B)

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The regulatory effect of GPX8 on Ca 2+ may be related to the inositol 1,4,5-triphosphate receptor (IP3R) effect, and the transmembrane domain (TMD) of GPX8 is thought to play a key role in the regulation of Ca 2+ signaling (Yoboue et al., 2017)