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Scientists use it as a model compound to investigate strategies for improving the bioavailability, half-life, and tissue targeting of peptide therapeutics

Perez-Carreras M, Del Hoyo P, Martin MA, Rubio JC, Martin A, Castellano G, Colina F, Arenas J, Solis-Herruzo JA (2003) Defective hepatic mitochondrial respiratory chain in patients with nonalcoholic steatohepatitis

This is especially relevant for people with type 2 diabetes using tirzepatide in addition to existing diabetes medications

Fold change in DiI-labelled LDL (c) and HDL (d) uptake of A-498 cells upon treatment with heparinases (0.1 U/mL), chondroitinase (0.1 U/mL), or both (blue), relative to uptake of untreated cells

What is compounded tirzepatide