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The prolonged half-life of GLP-1 analogs is achieved through several mechanisms, such as delayed absorption from the subcutaneous injection site, albumin binding, which shields the molecule from enzymatic degradation by DPP-4, and reduced renal clearance

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Vomiting Typical onset: 24 to 48 hours after injection, most common during dose increases

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However, the current studys use of Remo as a therapeutic agent to prevent liver fibrosis may be considered a limitation