A Randomized, Placebo-Controlled Trial of Cenicriviroc for Treatment of Nonalcoholic Steatohepatitis with Fibrosis
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It has been shown to upregulate the expression of genes involved in lipid clearance while activating AMP-activated protein kinase (AMPK) and downregulating sterol regulatory element-binding protein 1c (SREBP-1c), a transcription factor central to hepatic lipogenesis
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