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Retatrutide trials have additionally reported: Dysesthesia, such as tingling or altered skin sensation Injection-site reactions Decreased appetite Low blood pressure in some participants, particularly those using blood-pressure medication Because retatrutide is investigational, its final contraindications, warnings and approved safety label have not been established
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The most common adverse effects of retatrutide were gastrointestinal (GI) such as nausea, diarrhea, vomiting and constipation reported by 13-50% in the retatrutide groups compared with 35% in the dulaglutide group, and 13% in the placebo group
This doesn't mean Ozempic failed
Most patients were male (68%), White (73%), and were recruited from outside of the U.S
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