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More importantly, its durable clinical activity in patients who have progressed on prior anti-PD-1/PD-L1 or CAR-T-cell therapy underscores its potential to overcome adaptive resistance [341]
Given L-carnitine established role in facilitating mitochondrial -oxidation and its prior neuroprotective effects in adult ischemia models, it represents a biologically plausible candidate for investigation in neonatal brain injury
Standard treatment with levothyroxine addresses thyroid hormone deficiency but does not directly resolve metabolic complications or facilitate weight loss in many patients
Scientists have questioned whether differences in age, race, or starting weight might explain why some patients lose more weight than others
Peripheral neuropathy can result in symptoms such as numbness, tingling, and pain, particularly in the hands and feet
