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Elevated cAMP leads to activation of protein kinase A, which regulates key enzymes involved in triglyceride breakdown
There is a number of mechanisms of desensitization including: loss of receptor function through a decrease in receptor-coupled signaling components (e.g., G-proteins)
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In later childhood, patients can become severely obese unless their food intake is closely monitored by family and caregivers
However, the dual action may: Intensify this effect Make it more likely to occur Make it harder for the body to compensate 4
