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Mitochondrial GPX4 and DHODH suppress ferroptosis Mitochondria are essential for maintaining cellular viability, as they perform critical functions in bioenergetics, metabolism, and various signaling pathways
As many cysteine-containing proteins (transporters, receptors and enzymes) at extracellular surfaces or in extracellular fluids are prone to oxidation, their activity might be influenced by the thiol/disulphide redox microenvironment
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