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Pooled analysis reported no significant effect on not only total arrhythmia [RR=0.96, 95% CI (0.96, 1.05), p =0.36] ( Figure 2 ), but also its subtypes atrial fibrillation [RR=0.96, 95% CI (0.86, 1.07), p =0.43] ( Figure 3 ), atrial flutter [RR= 0.82, 95% CI (0.57, 1.19), p =0.30] ( Figure 3 ), atrial tachycardia [RR=0.64, 95% CI (0.20, 2.01), p =0.44)] ( Figure 3 ), sinoatrial node dysfunction [RR=0.74, 95% CI (0.44, 1.25), p =0.26] ( Figure 3 ), ventricular preterm systole [RR=1.42, 95% CI (0.62, 3.26), p =0.41] ( Figure 3 ), second degree AV block [RR=0.96, 95% CI (0.53, 1.72), p =0.88] ( Figure 3 ), complete AV block [RR=0.75, 95% CI (0.49, 1.17), p =0.21] ( Figure 3 ), ventricular fibrillation [RR=1.00, 95% CI (0.50, 2.02), p =1.00] ( Figure 3 ), ventricular tachycardia [RR=1.37, 95% CI (0.91, 2.08), p =0.13] ( Figure 3 ) from treatment with GLP-1RA versus placebo

Feelings of fullness may occur earlier during meals, which aligns with the medications intended effect but may require adjustments to eating habits

however, whether GLP-1RAs increase the risk of pancreatitis remains controversial (11)

Research reviews describe BPC-157 as a synthetic peptide derived from gastric proteins that appears to influence angiogenesis, collagen synthesis, fibroblast activity, nitric oxide pathways, and growth factor signaling