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Use of semaglutide and tirzepatide among people with multiple sclerosis [PMID: 42053291] Laboratory literature summary: Use of semaglutide and tirzepatide among people with multiple sclerosis
It can also increase the risk of kidney problems
This could explain why the activity of rhGPx3 mutant using H 2 O 2 as oxidizing substrate was in the same order of magnitude as that of human native GPx4 (34.8 U/mg) 9 and GPx4 mutant with all Cys converted to Ser (14.0 U/mg) 16 , while it was much lower than that of native GPx4 (64.6 U/mg) and the GPx4 mutant (24.6 U/mg) in the case of using PLPC-OOH as the oxidizing substrate
However, semaglutide remains highly effective and may be the better choice for certain patients
Semaglutide may have slightly higher rates of these effects in clinical trials, likely reflecting its greater potency
