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MD analysis Interatomic distances, root mean square deviations (RMSD), root mean square fluctuations, and centroids were computed using VMD1.9.4 55
Cancer development is slow (typically years or decades), community Dihexa use is relatively recent and small, and many users may not have long-term follow-up or may not associate a future cancer diagnosis with earlier Dihexa use
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Constipation affects 16-17%
To avoid a possible effect of food and water intake and physical activity, the meal plan and total daily fluid intake as well as physical activeness were kept constant during the study and the patients received a dietary advice with provided by a renal dietitian before the study commenced
