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This dose was used in the pivotal Phase 3 trials
This compound plays a vital role in our immune response and is responsible for triggering inflammation when the body is under attack
These drugs can lead to permanent sensorineural hearing loss (SNHL), affecting a substantial proportion of patients
Treatment of primary hepatocytes with the ER stressor tunicamycin (TM) upregulated UPR-responsive mRNAs, whereas etomoxir cotreatment suppressed this effect (Figure 1A)
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