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Reported or proposed issue Pregnancy, breastfeeding, children, liver disease, or cancer history Evidence source No direct human safety data Known or theoretical
Reduction of the selenotrisulfide derivative of glutathione to a persulfide analog by [PMID: 4400818] Laboratory literature summary: Reduction of the selenotrisulfide derivative of glutathione to a persulfide analog by glutathione reductase
Mitochondrial metabolic dysfunction reduces GSH production, impairs GPx4-mediated LPO clearance, and predisposes cells to ferroptosis (118)
Streptozotocin-induced diabetes in rats does not establish effectiveness for human diabetic cognitive impairment or diabetic neuropathy
Glycine: Small amino acid, big impact Glycine is the simplest amino acid in structure
