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Orforglipron is expected to face similar insurance challenges to other GLP-1 weight loss medications

Certain gut bacteria, like Bifidobacterium and Lactobacillus, have been associated with better weight management and reduced body fat

However, more severe side effects, such as pancreatitis and kidney problems, can occur

The Yale Center for Weight Management, a collaboration between Yale New Haven Health and Yale School of Medicine, brings together obesity medicine specialists across cardiology, gastroenterology, endocrinology, and orthopaedics, along with dietitians, psychologists, and exercise physiologists

This protocol is shown to acclimate the body to the effects of the medication and promote weight loss through reduced caloric intake