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To evaluate the effect of CI inhibition on growth, organoids were seeded as fragments in Matrigel and treated the following day with water (CTRL), 5 M 5FU, 3 mM metformin or a combination of 5FU and metformin for 72 h
Zwizek moe przyczynia si do obnienia poziomu enzymw wtrobowych , takich jak aminotransferaza asparaginianowa (AST), aminotransferaza alaninowa (ALT) czy glutamylotransferaza (GGT), co moe zmniejsza ryzyko rozwoju chorb tego narzdu
Es necesario hacer una evaluacin continua de la respuesta del paciente
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