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Tirzepatide itself has not been shown to cause direct nephrotoxicity

Zhang HD, Ding L, Liu K, Mi LJ, Zhang AK, Yu FY, et al

On a 0.5ml syringe, you will see numbers printed at 5, 10, 15, 20, 25, 30, 35, 40, 45, and 50

GLP-1 medications mimic the hormone and act on GLP-1 receptors

Omzo's weight-loss page states that "many members see up to 25% body weight reduction over time" - with the key qualifiers being "many" (not all), "up to 25%" (a ceiling, not an average), and "over time" (no specific timeframe defined)