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The most significant clinical data on retatrutide to date come from a Phase 2 randomised controlled trial published in the New England Journal of Medicine (2023), which evaluated the drug across multiple doses in adults with obesity

This powerful antioxidant exists in two different forms, including the oxidized and reduced states

Drinking enough water, eating more fiber, and staying active can also help

While some patients report increased skin dryness or sensitivity to touch, temperature, or topical products during treatment, these symptoms are not definitively linked to semaglutide and may have other causes that should be evaluated by a healthcare provider