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Until then, its cardioprotective effects remain promising but not conclusive (Nicholls et al

[16] [18] The addition of glucagon receptor agonism introduces further safety considerations requiring evaluation in Phase 3 trials, including potential effects on heart rate, blood pressure, and hepatic glucose output

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Data search PubMed searches were performed using relevant terms, including GLP-1, GLP-1 receptor agonists, Exenatide BID, Lixisenatide, Liraglutide, Albiglutide, Dulaglutide, Exenatide LAR, heart rate, and pulse rate