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According to the FDA label, semaglutide is contraindicated in patients with a personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia syndrome type 2, or prior serious hypersensitivity to semaglutide

If pancreatitis is suspected during GLP-1 agonist treatment, the medication should be stopped immediately as directed in the SmPC

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Diabetes, Other Risk Factors, and 12-yr Cardiovascular Mortality for Men Screened in the Multiple Risk Factor Intervention Trial

As of September 2025, Novo Nordisk has filed 140 lawsuits and issued 1K cease-and-desist letters against GLP-1 compounders