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Even a very mild state of dehydrationas little as 1% to 2% fluid losscan significantly impair your energy levels, reduce your ability to concentrate, and cause persistent headaches

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Lighter people (under 150 lbs) may find that 4 to 8 mg is sufficient for significant results, while heavier individuals (over 250 lbs) typically benefit from escalating to 12 mg

[10] Monitoring kidney function matters especially for older adults or those with preexisting kidney disease

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