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Although this impact in normal growth, strong evidence has been provided that IGF-1R is not an absolute requirement for normal growth, only partially (Baserga, 1999)

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This article is also available in Spanish: Tretinona Gua dermatolgica para pacientes Article References:

doi:10.1007/s11095-015-1652-z

7.4.2 Cumulative and interactive effects assessment Nanoparticles interact synergistically with other environmental stressors, including climate change, where changes in temperature and moisture affect nanoparticle behavior and toxicity profiles