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These associations underscore the role of lactate as an extracellular energy substrate in epigenetic regulation, particularly through histone lactylation
MetS and diabetes The worldwide prevalence of MetS and type 2 diabetes is increasing
The external adverse elements, such as cigarette smoking, physical damage, and microbiota influence, may cause keratinocytes damaged through excessive production of ROS(Plenkowska et al., 2020)
Pedraz-Petrozzi B, Elyamany O, Rummel C, Mulert C
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