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Individual responses vary significantly based on baseline cardiovascular fitness, existing heart conditions, and genetic factors
GLP-1 receptor agonists are transforming weight loss medicine, with semaglutide (Ozempic/Wegovy) delivering 12% weight loss and tirzepatide (Mounjaro/Zepbound) achieving 18% in clinical trials
than in other countries and the U.S
Pratley et al
Excessive caloric restriction risks nutritional deficiencies and metabolic adaptation that undermine research objectives
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