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Milk thistle (a liver-supporting herb) to help maintain glutathione levels

330,331 Increased glucose uptake by TAMs triggers the hexosamine biosynthetic pathway (HBP), enhancing O-GlcNAcylation of Cathepsin B, which promotes lysosomal secretion and fosters metastasis and chemoresistance

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With long term use (couple of months) can see the result

The best course of treatment for melasma would be sun avoidance, using a mineral-based sunscreen combined with topical skincare products with hydroquinone, Retinoids, Vitamin C, Kojic Acid, Niacinamide, Alpha Hydroxy Acids, Beta Hydroxy Acids, Azelaic Acid, and Arbutin