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Current evidence suggests GLP-1 receptor agonists have a neutral effect on fracture risk, though bone mineral density changes may occur indirectly through substantial weight loss
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El estudio AWARD-7 analiz la eficacia de dulaglutida en pacientes con DM2 y ERC moderada-severa (FGe medio 38ml/min/1,73m2)
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They measure acetoacetate excretion, which decreases as the body becomes more efficient at using ketones
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