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Metabolic Rewiring of Macrophages by CpG Potentiates Clearance of Cancer Cells and Overcomes Tumor-Expressed CD47-Mediated 'don't-Eat-Me' Signal
Infectious diseases causing autonomic dysfunction
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Efecto central : Acta a nivel de deseo y excitacin, no sobre el flujo sanguneo perifrico Va Perifrica (Inhibidores PDE5) Actan sobre la va NO/cGMP en el tejido vascular Efecto vasodilatador local No modulan el deseo ni la excitacin central Comparacin de Mecanismos | Caracterstica | PT-141 | Inhibidores PDE5 | |---------------|--------|-------------------| | Sitio de accin | SNC (hipotlamo) | Perifrico (vascular) | | Receptor | MC4R | PDE5 | | Efecto principal | Deseo/excitacin | Vasodilatacin | | Gnero | Ambos | Principalmente masculino | | Va admin
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