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PMID: 7994271

Introduction Strategies to prevent or ameliorate heart failure (HF) remain urgently needed ( Within the past 2 decades, glucagon-like peptide-1 (GLP-1) receptor agonists (RAs) have emerged as effective agents to improve glycaemic control in type 2 diabetes and to reduce body weight in people with overweight or obesity ( In this article, we review current evidence suggesting a potential benefit of GLP-1 RAs in HF as well as the current understanding of the putative mechanistic underpinnings

Phase I pilot (three healthy male volunteers, subcutaneous administration, 1996, PMID 8637402), increased facial, upper-body, and buttock pigmentation persisting approximately one week after cessation of dosing was reported alongside nausea and somnolence

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Hydrogen Energy 46 , 2359123602 (2021)