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Animal studies conducted in the Sekhar lab have shown that restoring glutathione levels by providing GlyNAC reverses glutathione deficiency, reduces oxidative stress and fully restores mitochondrial function in aged mice

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doi: 10.26402/jpp.2018.4.09

While lowering blood glucose is essential to preventing damage to the kidneys, nerves, eyes and other organs, it is the underlying insulin resistance more so than the high blood glucose level that is causing the cardiovascular problems