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Cautions and precautions include: History of pancreatitis (discontinue if pancreatitis is suspected) Type 1 diabetes or diabetic ketoacidosis (not indicated) Severe gastrointestinal disease including gastroparesis Gallbladder disease (increased risk with GLP-1 therapy) Diabetic retinopathy (monitor for worsening with rapid glycaemic improvement, particularly with semaglutide) Regarding renal impairment , most GLP-1 agonists (semaglutide, liraglutide, dulaglutide) require no dose adjustment
Also, slower stomach emptying can help reduce hunger between meals
What New Research Says GLP-1 medications such as Ozempic, Wegovy, and Zepbound have become some of the most widely prescribed drugs for weight loss and type 2 diabetes
While neither medication is free of side effects, the type of side effects differs
Published 2024 May 17
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