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Glucagon-like peptide-1 receptor agonists improve biomarkers of inflammation and oxidative stress: A systematic review and meta-analysis of randomised controlled trials
Its triple-receptor activity differentiates it from traditional single or dual-pathway peptide products
They also differ in their inactive ingredients and are not interchangeable drugs
Because the drug acts on gut hormone receptors and slows gastric emptying, the most commonly reported adverse effects in Phase 2 trials include: Nausea (particularly during dose escalation) Vomiting Diarrhoea Constipation Decreased appetite These effects were generally described as mild to moderate in severity and tended to diminish over time
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