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A newly published clinical investigation in the British Journal of Anaesthesia (May 2025 issue) reveals compelling evidence linking glucagon-like peptide-1 receptor agonists (GLP-1RAs) to impaired gastric emptying (IGE)

While oral and injectable routes dominate consumer markets, intranasal delivery is increasingly favored in experimental pharmacology for bypassing hepatic first-pass metabolism and ensuring more rapid compound absorption into systemic circulation

Human trials showed improved cardiovascular outcomes and reduced mortality over 12-year follow-up [4]

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