can vitamin b12 injections cause headaches B Deficiency: Symptoms, Causes and Vaccine Why Do I Feel Worse

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A 2019 randomized controlled trial of lipotropic injections (methionine, inositol, choline, B12) versus saline placebo in 120 participants on ad libitum diets found 0.8 kg (1.76 pounds) difference at 12 weeks, not statistically significant (p=0.18) (Karbalay-Doust et al., Journal of Research in Medical Sciences , 2019)

Saline solution (0.9% sodium chloride) is sometimes used but has disadvantages

If this applies to you, speak to a healthcare professional before restarting treatment on your own