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Available from: Rentzeperi E, Pegiou S, Koufakis T, et al Sex differences in response to treatment with glucagon-like peptide 1 receptor agonists: opportunities for a tailored approach to diabetes and obesity care

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This triggers a dual effect on: Glucose-Dependent Secretion: The rise in cAMP activates Protein Kinase A (PKA) and Epac (Exchange Protein directly activated by cAMP)

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