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Subsequent experiments indicated that control grafts showed features associated with exacerbated ferroptosis, including elevated LPO levels and suppression of the antioxidant system

Meanwhile, it is worth noting that although the current data do not show a significant increase in the risk of pancreatitis, long-term follow-up should still focus on the potential risks of pancreatitis and thyroid C-cell tumors, especially as GCGR activation may affect pancreatic exocrine function ( 4.2 Combination therapy strategies Combining triple receptor agonists with other pharmacological agents holds promise for synergistic metabolic benefits in MASLD management

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Long term effects are being studied