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Rare but serious side effects include severe allergic reactions (hives, difficulty breathing, swelling of face or throat) and Clostridioides difficilerelated diarrhea (frequent, foulsmelling stools, fever, stomach cramps)
The 12.5 to 15 mg band adds modestly to average weight loss but widens the high-response tail
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But hormone therapy has been found to reduce osteoporosis risk in some patients
Kazi reported grants from the National Heart, Lung, and Blood Institute, American Heart Institute, Agency for Healthcare Research and Quality, Patient-Centered Outcomes Research Institute, and Institute for Clinical and Economic Research outside the submitted work
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