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Most patients can minimize these side effects by starting with a low dose and gradually titrating upward
Led by Editor-in-Chief Anna M
Medical literature does not report safety or efficacy data for this combination, leaving prescribing decisions in the absence of evidence
Other important safety considerations include maintaining adequate hydration to prevent acute kidney injury if experiencing severe gastrointestinal symptoms, monitoring for mood changes or suicidal ideation (particularly with Wegovy), and considering retinopathy monitoring in people with type 2 diabetes
In this issue, Buckley et al ( compare retinal outcomes of over 3000 people initiating tirzepatide with a matched group of unexposed individuals
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