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Slower dose escalation or short treatment pauses may improve tolerance 9,15
Clin Ophthalmol
That said, tolerability is broadly similar across the three compounds: gastrointestinal adverse events dominate, and slow titration is the universal strategy for managing them
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Semaglutide was previously approved under the brand names Rybelsus (oral) and Ozempic (lower-dose injection) for the treatment of type 2 diabetes
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