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In a 23-week randomized clinical trial in humans, individuals taking AOD-9604 at 1 mg daily had an average of 2.8 kg weight reduction compared to a 0.8 kg weight reduction in those taking a placebo
Beyond that, failing to rotate can cause skin irritation, bruising, and increased pain at the injection site
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A randomised controlled trial involving over 1,900 people living with obesity showed that 7% of participants discontinued their medication due to adverse events and side effects
Funding The authors are grateful to King Saud University, Riyadh, Saudi Arabia, for funding this work through the Ongoing Research Funding program - Research Chairs (ORF-RC-2025-5100)
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