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A phase 2 randomised controlled trial published in the New England Journal of Medicine (2023) reported substantial weight loss and improvements in glycaemic parameters, though the trial was conducted in a closely monitored clinical setting with defined eligibility criteria

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[4] Clinical assessment should focus on identifying the cause of elevated levels rather than assuming toxicity from supplementation alone

Safety Profile and Considerations BPC-157 demonstrates a remarkably benign safety profile in preclinical research