The rationale behind this phenomenon pertains to the function of CAFs in regulating ECM remodelling within the TME
I often combine LDN with IV therapies including glutathione and vitamin C
Brigatinib, a newly discovered AXL inhibitor, suppresses AXL-mediated acquired resistance to osimertinib in EGFR-mutated non-small cell lung cancer
Pro-Hyp, Hyp-Gly) act as signaling molecules that stimulate fibroblast activity and increase endogenous collagen synthesis Supports reductions in collagenase/gelatinase enzyme activity, which helps limit connective tissue breakdown and improves skin elasticity and hydration Best For: Skin elasticity/anti-aging support, joint pain and cartilage maintenance, and general connective tissue and tendon-ligament recovery Typical Protocol: 1 g/day has been used in trials for skin hydration and elasticity (RCT, PMC6073484), while 5-15 g/day is the range studied for joint health and muscle recovery, with 15 g/day showing greater benefit than 5 g/day (systematic review, PMC8521576)
Lean protein, Greek yogurt, cottage cheese, eggs, tofu, beans, or protein shakes are easy wins