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Always check the technical data sheet for solvent recommendations, particularly for less common compounds with unusual solubility profiles

JAMA Network Open, 9(5), e2612133

While generally safe, they can cause nausea, bloating, vomiting, and diarrhoea, and in rare cases may lead to stomach paralysis

however, most studies have been of modest duration and conducted in diabetes populations rather than dedicated HF cohorts as continued pharmacovigilance and longer-term HF-specific safety data are needed